Offenzeller M, et al. Biosynthesis of the unusual amino acid (4R)-4-[(E)-2-butenyl]-4-methyl-L-threonine of cyclosporin A. J. Biol. Chem. 268: 26127-26134, 1993. PubMed: 8253730
Ruegger A, Kuhn M. Dihydrocyclosporin C. US Patent 4,108,985 dated Aug 22 1978
Harri E, Ruegger A. Organic compounds. US Patent 4,117,118 dated Sep 26 1978
Traber RP, et al. Cyclosporin derivatives, their production and pharmaceutical compositions containing them. US Patent 4,288,431 dated Sep 8 1981
Weber G, et al. The peptide synthetase catalyzing cyclosporine production in Tolypocladium niveum is encoded by a giant 45.8-kilobase open reading frame. Curr. Genet. 26: 120-125, 1994. PubMed: 8001164
Weber G, Leitner E. Disruption of the cyclosporin synthetase gene of Tolypocladium niveum. Curr. Genet. 26: 461-467, 1994. PubMed: 7874740
von Arx JA. Tolypocladium, a synomym of Beauveria. Mycotaxon 25: 153-158, 1986.
Kempken F, et al. A unique repeated DNA sequence in the cyclosporin-producing strain of Tolypocladium inflatum (ATCC 34921). Exp. Mycol. 19: 305-313, 1995. PubMed: 8574905
Agathos SN, Lee J. Mathematical modeling of the production of cyclosporin A by Tolypocladium inflatum: effect of L-valine. Biotechnol. Prog. 9: 54-63, 1993. PubMed: 7763411
Kempken F, Kuck U. Evidence for circular transposition derivatives from the fungal hAT-transposon Restless. Curr. Genet. 34: 200-203, 1998. PubMed: 9745022
Lee TH, et al. Development of a cell-loaded biosupport separator for continuous immobilized-cell perfusion culture. Biotechnol. Prog. 15: 267-272, 1999. PubMed: 10194403
Ruegger A, et al. Cyclosporin A, a Peptide Metabolite from Trichoderma polysporum (Link ex Pers.) Rifai, with a remarkable immunosuppressive activity. Helv. Chim. Acta 59: 1075-1092, 1976. PubMed: 950308
Traber R, et al. New cyclopeptides from Trichoderma polysporum (Link ex Pers.) Rifai: cyclosporins B, D and E. Helv. Chim. Acta 60: 1568-1578, 1977. PubMed: 561044
Hoppert M, et al. Structure and localization of cyclosporin synthetase, the key enzyme of cyclosporin biosynthesis in Tolypocladiium inflatum. Arch. Microbiol. 176: 285-293, 2001. PubMed: 11685373
Lee J, Agathos SN. Effect of amino acids on the production of cyclosporin A by Tolypocladium inflatum. Biotechnol. Lett. 11: 77-82, 1989.
Aarnio TH, Agathos SN. Production of extracellular enzymes and cyclosporin by Tolypocladium inflatum and morphologically related fungi. Biotechnol. Lett. 11: 759-764, 1989.
Windhofer F, et al. Ds-like restless deletion derivatives occur in Tolypocladium inflatum and two foreign hosts, Neurospora crassa and Penicillium chrysogenum. Fungal Genet Biol 35: 171-182, 2002. PubMed: 11848679
|